Campto is a highly specialized antineoplastic (chemotherapy) medication containing Irinotecan Hydrochloride. It belongs to the class of drugs known as "topoisomerase I inhibitors." It works by interfering with the DNA replication process in cancer cells; specifically, it traps the topoisomerase I enzyme, causing irreversible DNA strand breaks that lead to the death of rapidly dividing cancer cells. Campto is a cornerstone of modern oncology, particularly for treating advanced gastrointestinal malignancies.
Product Type: Cytotoxic Antineoplastic (Chemotherapy)
Active Ingredient: Irinotecan Hydrochloride (40mg / 2ml)
Manufacturer: Pfizer (Original Brand) / Generic Equivalents Available
Pack Size: Single-dose Type I Glass Vial
Route: Intravenous (IV) Infusion Only
Availability: Strictly Prescription Required (POM) — Hospital/Oncology Use Only
Suitable For: Adults with advanced colorectal cancer
Campto is primarily used in specialized "cocktail" regimens (such as FOLFIRI) to treat aggressive cancers:
Advanced Colorectal Cancer: First-line treatment in combination with 5-fluorouracil (5-FU) and folinic acid.
Second-Line Therapy: Used as a single agent for patients whose metastatic colorectal cancer has returned or progressed after initial 5-FU-based therapy.
Small Cell Lung Cancer: Sometimes used off-label in specialized protocols for refractory lung cancer.
Gastric & Esophageal Cancers: Utilized in specific combinations for advanced gastroesophageal malignancies.
Severe Diarrhea: Campto can cause life-threatening diarrhea. Early Diarrhea (within 24 hours) is often accompanied by sweating and abdominal cramps and is treated with Atropine. Late Diarrhea (after 24 hours) can lead to severe dehydration and must be treated immediately with high-dose Loperamide (Imodium). Neutropenia: This drug can severely lower your white blood cell count, making you highly susceptible to life-threatening infections. Cholinergic Syndrome: Some patients experience sudden salivation, tearing, and low heart rate during the infusion. Pregnancy: This medication is highly toxic to a developing fetus. Effective contraception is mandatory for both men and women during and for months after treatment.
Campto must be prepared and administered by qualified oncology nurses or doctors in a specialized clinical setting.
Administration Protocols:
Dilution: The 40mg concentrate must be diluted in either 5% Dextrose (preferred) or 0.9% Sodium Chloride to a final concentration of $0.12mg/ml$ to $2.8mg/ml$.
Infusion Time: The diluted solution is typically infused over 30 to 90 minutes.
Dosing Schedule: Usually given once every 3 weeks or once weekly for 4 weeks followed by a rest period, depending on the protocol.
Pre-medication: Patients are often given anti-nausea medications (like Ondansetron) and sometimes Atropine before the infusion starts.
Beyond diarrhea and low blood counts, patients may experience significant nausea, vomiting, hair loss (alopecia), and extreme fatigue. Temporary liver enzyme elevations or skin rashes may also occur. If you develop a fever over 38°C, sudden shortness of breath, or uncontrollable diarrhea, contact your oncology team immediately.
Store the unopened vial at room temperature below 25°C, protected from light. Do not freeze. Once diluted, the solution is stable for up to 6 hours at room temperature or 24 hours in a refrigerator, but it is best used immediately to ensure sterility. Keep out of reach of children.
Q: Why do I need to keep "Imodium" at home?
A: Because "Late Diarrhea" can start suddenly days after your treatment. Your oncologist will likely give you a specific "Emergency Diarrhea Protocol" involving Loperamide to start the moment you have your first loose stool.
Q: Will I lose my hair?
A: Thinning or total hair loss is very common with Campto, but it is almost always reversible once the treatment cycles are completed.
Q: Can I get my "Routine Vaccinations" while on Campto?
A: No. Avoid "Live" vaccines (like Yellow Fever or MMR) while on chemotherapy, as your immune system is too weak to handle them. Always consult your oncologist first.
Q: Why "40mg" if my dose is higher?
A: Chemotherapy is calculated based on "Body Surface Area" ($mg/m^2$). Your pharmacist will combine multiple vials (e.g., three 40mg vials for a 120mg dose) to match your exact prescription.
Authentic Campto (by Pfizer) is supplied by Sanlive Pharmacy to registered oncology centers and hospitals. We maintain strict handling and storage protocols to ensure the integrity of these sensitive cytotoxic medications.
Authentic Pfizer (Original) oncology-grade stock.
Expert clinical support for dilution and dosing calculations.
Licensed pharmacists available for oncology-safety consultations.
Specialized, secure delivery to medical facilities across Nigeria.
Order Campto 40mg from Sanlive Pharmacy today for professional-grade, specialized cancer care.
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