Engerix-B is a non-infectious, recombinant DNA vaccine developed to provide long-term immunity against the Hepatitis B virus (HBV). Manufactured by GlaxoSmithKline (GSK), it contains purified surface antigens of the virus. By stimulating the body to produce its own antibodies, it prevents the severe liver complications associated with chronic Hepatitis B, including cirrhosis and liver cancer.
Product Type: Recombinant Viral Vaccine
Manufacturer: GlaxoSmithKline (GSK)
Active Ingredient: Hepatitis B Surface Antigen (HBsAg) — 20mcg/1.0ml
Pack Size: 1.0ml Pre-filled Syringe or Single-dose Vial
Route: Intramuscular (IM) Injection
Availability: Strictly Prescription/Clinical Administration
Suitable For: Adults and adolescents aged 20 and older (High-strength dose)
Engerix-B is indicated for active immunization against Hepatitis B infection caused by all known subtypes. It is particularly essential for:
Healthcare Workers: Protecting doctors, nurses, and lab technicians who are at high risk of exposure to infected blood.
High-Risk Individuals: Protecting people with multiple sexual partners, those traveling to high-prevalence areas, or individuals living with a Hepatitis B-positive person.
Chronic Disease Management: Patients with chronic kidney disease (including those on dialysis) or chronic liver disease.
Universal Adult Vaccination: Any adult seeking to prevent a life-long, potentially fatal liver infection.
Yeast Allergy: Do not take Engerix-B if you have a history of severe allergic reactions to yeast, as the vaccine is produced using genetically engineered yeast cells. Acute Illness: If you have a high fever or severe infection, wait until you are fully recovered before getting the injection. Not a Cure: This vaccine cannot treat a person who is already chronically infected with the Hepatitis B virus. Screening: At Sanlive Pharmacy, we recommend a "Hepatitis B Surface Antigen" blood test before starting the series to confirm you are not already a carrier.
Engerix-B 20mcg must be administered by a licensed healthcare professional, usually in the deltoid muscle (upper arm). Do not inject into the buttock, as this significantly reduces the vaccine's effectiveness.
The Standard 3-Dose Schedule:
First Dose: At the elected date.
Second Dose: 1 month after the first dose.
Third Dose: 6 months after the first dose.
Accelerated Schedule: For rapid travel protection, a 0, 1, and 2-month schedule may be used, with a booster at 12 months.
Most side effects are mild and resolve within 48 hours. They include soreness, redness, or a hard lump at the injection site. Some patients may experience a mild headache, fatigue, or a low-grade fever. Fainting can occur after any injection; it is advised to remain seated for 15 minutes after the shot. If you experience swelling of the face, difficulty breathing, or a widespread rash, seek emergency medical care immediately.
Cold Chain Maintenance: Engerix-B is extremely sensitive to temperature. It must be stored in a medical refrigerator between 2°C and 8°C. It must never be frozen. If the vaccine is frozen, the antigen structure is destroyed, and the vaccine becomes useless. Keep the vial in the outer carton to protect it from light.
Q: Why is this version 20mcg?
A: The 20mcg dose is the standard strength for adults (20 years and older). Children and adolescents (up to age 19) typically receive a 10mcg dose (Engerix-B Paediatric).
Q: Do I need a "Booster" later in life?
A: For most healthy individuals, the 3-dose series provides lifelong protection. However, immunocompromised patients or those on dialysis may need periodic testing and boosters.
Q: Can I get this while pregnant?
A: Yes. Hepatitis B vaccination is generally considered safe during pregnancy and is highly recommended if the mother is at risk of infection, to prevent passing the virus to the baby.
Q: Can I drink alcohol after the shot?
A: While there is no direct interaction, it is best to avoid heavy alcohol for 24 hours to allow your immune system to focus on responding to the vaccine without additional stress.
Engerix-B 20mcg (by GSK) is available at Sanlive Pharmacy for professional administration. We maintain a rigorous Cold Chain protocol to ensure every dose is potent and effective when it reaches you.
Verified authentic GSK vaccine stock.
Certified cold-chain storage with 24/7 temperature monitoring.
Professional administration by licensed healthcare providers.
Full vaccination schedule tracking and digital reminders.
Contact Sanlive Pharmacy today to start your Hepatitis B vaccination series and ensure your long-term liver health.
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