Evorel 100 is a high-dose, matrix-type transdermal patch containing Estradiol hemihydrate, the chemically identical form of the natural female hormone $17\beta$-estradiol. It works through a continuous systemic delivery mechanism: the hormone is embedded directly into the adhesive matrix of the patch and is absorbed through the skin into the bloodstream at a constant rate of 100 micrograms every 24 hours. This bypasses the "first-pass" metabolism of the liver, providing stable hormonal levels that effectively suppress severe menopausal symptoms and prevent bone density loss.
In Nigeria, Evorel 100 (by Theramex/Janssen) is a premier clinical choice for women requiring intensive Hormone Replacement Therapy (HRT) for surgical menopause or severe vasomotor symptoms. It is available through gynecology clinics and registered pharmacies like Sanlive Pharmacy, ensuring you receive authentic, laboratory-verified patches stored in cool, dry conditions (below 25°C). This is critical because the adhesive matrix is heat-sensitive; exposure to the Nigerian sun or high humidity can cause the estradiol to crystallize or the adhesive to fail, leading to inconsistent dosing and a sudden return of "hot flashes" and night sweats.
Important: This is a high-potency hormonal device. The "Twice-Weekly" Rule: Each Evorel 100 patch lasts for 3 to 4 days; you must change the patch exactly twice a week (e.g., every Monday and Thursday) to maintain protective hormone levels. The "Progesterone" Note: If you still have your uterus, you must take a separate progestogen (like Utrogestan) alongside Evorel to protect the lining of the womb from overgrowth. The "Blood Clot" Warning: While transdermal patches have a lower risk than oral tablets, estrogen still increases the risk of Venous Thromboembolism (VTE); you must report any sudden leg swelling or chest pain immediately.
Evorel 100 Patches are primarily used for:
Relieving Severe Menopausal Symptoms: Eliminating intense hot flashes, night sweats, and sleep disturbances.
Treating Surgical Menopause: Replacing hormones immediately following the removal of the ovaries.
Osteoporosis Prevention: Protecting bone density in high-risk postmenopausal women.
Managing Vaginal Atrophy: Reducing the thinning and dryness of urogenital tissues.
Providing Liver-Friendly Estrogen: Reducing the risk of gallbladder issues and blood pressure spikes compared to oral HRT.
Offering Stable 24-Hour Delivery: Preventing the "mood swings" and headaches associated with daily pill fluctuations.
Supporting Cardiovascular Health: In specific early-menopause cases, maintaining healthy lipid profiles under specialist care.
This medication is intended for:
Women with severe estrogen deficiency symptoms that lower-dose patches (Evorel 25 or 50) failed to control.
Patients under the active, regular supervision of a Gynecologist or Endocrinologist.
Not recommended for: Women with a history of Breast Cancer or other estrogen-sensitive tumors. It is strictly contraindicated for individuals with undiagnosed vaginal bleeding, active blood clots (DVT/PE), or severe untreated high blood pressure. Use with extreme caution if you have a history of Endometriosis or Migraines with Aura. Consult our pharmacist if you are using Skin Creams or Oils near the application site, as these will prevent the patch from sticking. Consult your doctor if you smoke, as nicotine increases the cardiovascular risks of any hormone therapy.
Administered via Transdermal route (applied to the skin).
The "Waist-Down" Rule: Apply the patch to a hairless, clean, dry area of skin below the waist (usually the thigh or buttock); never apply the patch on or near the breasts.
The "Rotate" Tip: Always place each new patch on a different area of skin to prevent irritation; wait at least one week before using the exact same spot again.
Consistency is Vital: Change your patch on your two designated "patch days" each week; if you forget, change it as soon as you remember and then stick to your original schedule.
The "Bath/Shower" Note: You can bathe, shower, and swim with the patch on; however, if it falls off, apply a new one immediately and continue with your normal schedule.
The "Disposal" Rule: Fold the used patch in half (adhesive side together) and discard it safely out of reach of children and pets; it still contains active hormones.
Evorel 100 is highly effective but significantly shifts the hormonal balance, potentially causing:
Skin Irritation: Redness or itching at the site where the patch was applied (very common).
Breast tenderness or slight enlargement.
Breakthrough Bleeding: Spotting is common in the first 3 to 6 months of treatment.
Headaches or mild nausea.
Water retention (bloating) and mood changes.
Rare but serious: Blood Clots or sudden increase in blood pressure.
Rare: Gallbladder stones or migraine worsening.
Seek medical advice immediately if you experience a new lump in your breast, sudden severe headaches, yellowing of the skin (jaundice), or pain and swelling in one leg.
Theramex / Janssen-Cilag – Global leaders in women's health, ensuring that every Evorel 100 matrix patch meets international standards for sterile adhesive stability and estradiol purity.
100% Authentic: Guaranteed original stock with verified NAFDAC and batch-tracking numbers.
Optimal Storage: Kept in a climate-controlled environment to protect the matrix adhesive and hormone potency.
Professional Counseling: Advice from licensed pharmacists on "Patch Rotation" and managing breakthrough bleeding.
Secure Delivery: Fast and discreet shipping to your home or office across Nigeria.
Can I cut the patch in half?
No. Cutting a matrix patch can damage the delivery system and cause the hormone to be released all at once or not at all. If the dose is too high, your doctor will prescribe Evorel 50 instead.
Where is the "Best Place" to put it?
The lower back, buttocks, or upper thighs are best. Avoid the waistline where tight clothing or belts might rub the patch off.
Does it cause "Weight Gain"?
Most women experience temporary water retention (bloating) when starting. True fat gain is usually related to the metabolic changes of menopause itself rather than the HRT patch.
Where can I purchase Evorel 100 in Nigeria?
You can fill your gynecology or specialist prescription for verified Evorel at Sanlive Pharmacy & Stores for guaranteed product integrity and professional hormonal health support.
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