IMURAN (AZATHIOPRINE) 25MG TABLETS – SELECTIVE IMMUNOSUPPRESSIVE THERAPY

Imuran contains Azathioprine, a specialized "pro-drug" belonging to the antimetabolite class. Once ingested, it is rapidly converted into the active metabolite 6-mercaptopurine (6-MP). It works by interfering with the synthesis of DNA and RNA, specifically targeting the proliferation of T and B lymphocytes (white blood cells) that drive the body's immune response. By "quieting" an overactive immune system, Imuran prevents the body from attacking its own tissues or rejecting a transplanted organ, while allowing for a reduction in long-term steroid use.

In Nigeria, Imuran 25mg (by Aspen/GSK or quality generics) is the gold-standard clinical choice for managing autoimmune disorders and organ transplants. It is available through specialized pharmacies like Sanlive Pharmacy to ensure patients receive authentic, high-stability tablets manufactured under strict international standards and stored in cool, dry environments to maintain the molecular integrity of the 25mg dose.

Important: This is a high-precision, prescription-only medication. The "Blood" Rule: Imuran can significantly lower your white blood cell and platelet counts; you must have regular blood tests (Full Blood Count) to monitor for "Bone Marrow Suppression." The "Infection" Warning: Because this medicine lowers your immunity, contact our pharmacist or your doctor immediately if you develop a fever, sore throat, or unusual bruising. The "Sun" Warning: Imuran increases your skin's sensitivity to UV rays; you must wear SPF 50+ sunscreen and protective clothing to prevent skin cancer risk. Do not use if you have a known hypersensitivity to Azathioprine or 6-Mercaptopurine.

Key Uses & Benefits

Imuran 25mg Tablets are primarily used to:

• Prevent Organ Transplant Rejection (Kidney, Heart, and Liver)

• Treat Rheumatoid Arthritis that has not responded to other medications

• Manage Systemic Lupus Erythematosus (SLE) and severe inflammatory disorders

• Treat Inflammatory Bowel Disease (IBD), including Crohn’s Disease and Ulcerative Colitis

• Manage Autoimmune Hepatitis to reduce liver inflammation

• Act as a "Steroid-Sparing" Agent, allowing patients to lower their dose of Prednisolone

• Treat rare autoimmune conditions like Myasthenia Gravis and Pemphigus Vulgaris

Who Should Use Imuran 25mg?

This product is suitable for:

• Patients requiring long-term immune suppression for chronic inflammatory diseases

• Transplant recipients whose new organs must be protected from immune attack

• Individuals who have suffered severe side effects from high-dose steroids

Not recommended for: Individuals with severe pre-existing bone marrow suppression or those who have previously experienced a severe allergic reaction to Imuran. It is strictly contraindicated for patients currently taking Allopurinol (for gout) unless the Imuran dose is reduced to 25% of the normal amount, as Allopurinol can cause Imuran levels to become toxic. Use with extreme caution in patients with known "TPMT" enzyme deficiency. Consult our pharmacist if you are taking ACE inhibitors (for blood pressure) or Warfarin. Consult your doctor if you are pregnant; it should only be used if the benefit clearly outweighs the potential risk to the fetus.

Suggested Clinical Usage

• Take exactly as prescribed; the starting dose is calculated based on body weight (typically 1mg to 3mg per kg).

• The "Meal" Tip: Taking your dose after a meal or at bedtime can help reduce the common side effect of nausea.

• Swallow the tablet whole with a glass of water; do not crush or chew it.

• Consistency is Vital: Imuran is a slow-acting drug; it may take 6 to 12 weeks of daily use to see a significant clinical improvement in your condition.

• The "Lab" Rule: During the first 8 weeks of treatment, you will typically need blood tests every week to ensure your bone marrow is healthy.

• The "Vaccine" Warning: While on Imuran, you should avoid "Live" vaccines (like Yellow Fever or Oral Polio) as they can cause serious infections.

• If a dose is missed, take it as soon as you remember that day, but skip it if it is almost time for your next dose—never "double up" to 50mg.

Common Side Effects

Imuran is highly effective, but because it modulates the immune system and bone marrow, some individuals may experience:

• Nausea or vomiting (especially during the first few weeks)

• Loss of appetite or mild stomach pain

• Increased sensitivity to the sun (Photosensitivity)

• Temporary thinning of the hair

• Rare but serious: Leukopenia (low white blood cells increasing infection risk)

• Rare: Liver inflammation (indicated by yellowing of the eyes or dark urine)

• Rare: Pancreatitis (severe upper abdominal pain)

• Rare: An increased long-term risk of skin cancer or lymphoma

Seek immediate medical attention if you experience a sudden high fever, severe persistent vomiting, yellowing of the skin, or unusual bleeding/bruising.

Manufacturer

Aspen Pharmacare (Global) or GSK – World leaders in specialized pharmaceutical care, ensuring that Imuran is produced with high-purity Azathioprine for reliable and predictable immunosuppression.

Why Buy Imuran from Sanlive Pharmacy?

• 100% authentic specialized medication—guaranteed original stock with verified batch numbers.

• Guaranteed high-quality tablets stored in optimal, climate-controlled conditions to protect the drug.

• Professional counseling from licensed pharmacists on "Drug-Drug Interactions" and sun protection.

• Fast and discreet delivery to your home, office, or clinic across Nigeria.

Frequently Asked Questions (FAQs)

Why do I feel sick to my stomach after taking it?

Nausea is common at the start. Splitting your dose or taking it with your largest meal usually helps. Most people find that this feeling goes away after a few weeks as the body adjusts.

Can I stop taking it once I feel better?

No. Imuran does not "cure" autoimmune diseases; it keeps them in "remission" (sleep). Stopping it suddenly can cause a severe flare-up of your original disease or organ rejection.

Is it safe to go out in the sun?

Yes, but you must be careful. Imuran makes your skin much more likely to burn and increases the risk of skin cancer over many years. Always use high-quality sunscreen and stay in the shade when possible.

Where can I purchase Imuran 25mg in Nigeria?

You can fill your rheumatology, gastroenterology, or transplant prescription for Imuran at Sanlive Pharmacy & Stores for guaranteed product integrity and professional specialized support.