Perizol contains Methimazole (also known internationally as Thiamazole). It is a highly effective antithyroid medication belonging to the thionamide class. It is specifically engineered to treat hyperthyroidism (an overactive thyroid gland) by inhibiting the enzyme thyroid peroxidase. This action prevents the thyroid gland from attaching iodine to tyrosine, effectively blocking the synthesis of the primary thyroid hormones, Thyroxine ($T_4$) and Triiodothyronine ($T_3$).
Product Type: Antithyroid Agent (Thionamide)
Active Ingredient: Methimazole / Thiamazole (10mg)
Manufacturer: Various (Available via Sanlive Pharmacy and clinical distributors)
Pack Size: 30, 50, or 100 Tablets
Route: Oral
Availability: Strictly Prescription Required (POM) — Endocrinologist consultation mandatory
Suitable For: Adults and children with hyperthyroidism
The 10mg strength is frequently used during the initial "loading" phase or for moderate to severe hyperthyroidism:
Graves' Disease: The primary treatment for autoimmune overactivity of the thyroid.
Toxic Multinodular Goiter: Managing overactive nodules that produce excess hormones.
Thyroid Storm: Used in high-dose emergency protocols to rapidly suppress hormone production.
Pre-Surgical Stabilization: Ensuring a patient is "euthyroid" (normal levels) before undergoing a thyroidectomy.
Radioactive Iodine Prep: Controlling symptoms before or after $I^{131}$ therapy.
Agranulocytosis: This is a rare but life-threatening side effect where your white blood cell count drops dangerously low. If you develop a sudden sore throat, fever, or mouth ulcers, stop Perizol immediately and seek emergency medical care. Liver Health: Methimazole can cause severe liver inflammation (hepatitis) or bile duct blockage. Notify your doctor if you notice yellowing of the eyes (jaundice), dark urine, or severe itching. Pregnancy Alert: Perizol is generally avoided during the first trimester of pregnancy because it can cause birth defects. Propylthiouracil (PTU) is usually preferred during early pregnancy. Low Thyroid (Hypothyroidism): If the dose is too high, you may experience extreme fatigue, weight gain, and cold intolerance.
For maximum efficacy, Perizol must be taken consistently to keep thyroid hormone production suppressed.
Standard Dosage:
Initial Dose: Typically 30mg to 60mg daily (often taken as 10mg three times daily) depending on the severity of the hyperthyroidism.
Maintenance Dose: Usually 5mg to 15mg daily once thyroid levels have stabilized.
Application Tips:
Consistency: Take your tablet at the same time every day, either with or without food.
Blood Tests: You will require frequent "Thyroid Function Tests" ($T_3, T_4, TSH$) every 4 to 6 weeks during the start of therapy to ensure your dose is correct.
Do Not Stop Suddenly: Stopping treatment without medical advice can cause your hyperthyroid symptoms (like rapid heart rate) to return aggressively.
Common side effects include mild skin rash, itching, hives, nausea, vomiting, or joint pain. Some patients may experience temporary hair loss or a change in their sense of taste. If you experience severe abdominal pain or unusual bruising/bleeding, seek medical attention immediately.
Store in a cool, dry place below 25°C, protected from light and moisture. Keep the tablets in their original packaging until needed. Keep out of reach of children.
Q: Is "Thiamazole" different from "Methimazole"?
A: No. They are two names for the exact same active ingredient. "Thiamazole" is the international name used in many countries, including Nigeria and Europe.
Q: How long until I feel better?
A: Perizol stops the production of new hormones, but it doesn't stop the hormones already in your blood. It may take 1 to 3 weeks for symptoms like tremors and sweating to improve.
Q: Can I take it while "Breastfeeding"?
A: Yes, in moderate doses (up to 20mg daily), Methimazole is considered safe for breastfeeding mothers, but the infant's thyroid function should be monitored.
Q: Does it interact with "Warfarin"?
A: Yes. Hyperthyroidism and antithyroid drugs can change how your blood clots. If you are on blood thinners, your doctor will need to monitor your INR more closely.
Authentic Perizol 10mg is available at Sanlive Pharmacy with a valid prescription. We provide professional endocrine counseling and can assist you in tracking your thyroid lab results to ensure your dose is optimized for your recovery.
Authentic, clinical-grade antithyroid stock.
Expert guidance on monitoring for "Sore Throat/Fever" safety.
Licensed pharmacists available for clinical drug-interaction checks.
Fast, reliable delivery nationwide across Nigeria.
Order Perizol 10mg from Sanlive Pharmacy today for professional-grade thyroid management.
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