Phytomenadione (Vitamin K1) is a synthetic lipid-soluble analogue of naturally occurring Vitamin K. It is a critical cofactor in the hepatic synthesis of blood clotting factors II (prothrombin), VII, IX, and X. In the absence of sufficient Vitamin K, these factors remain inactive, leading to a high risk of spontaneous bleeding. Phytomenadione works by restoring the body’s ability to produce these essential proteins, effectively reversing bleeding tendencies caused by nutritional deficiency, malabsorption, or the overdose of oral anticoagulants like Warfarin.
In Nigeria, Phytomenadione 10mg/1ml (commonly known as Konakion) is a life-saving clinical choice for emergency and pediatric care. It is available through registered pharmacies like Sanlive Pharmacy to ensure medical facilities receive authentic, high-stability ampoules manufactured under strict pharmaceutical standards and stored in light-protected, temperature-controlled environments to prevent the degradation of the light-sensitive Vitamin K molecule.
Important: This is a specialized, prescription-only injectable medication. The "Light" Rule: Phytomenadione is highly sensitive to light; the ampoules must be kept in their original carton until the moment of use. The "IV Warning": Intravenous (IV) administration carries a rare but serious risk of severe allergic-like reactions (anaphylaxis). IV doses must be given very slowly or diluted as per clinical protocols. Do not use if the solution is cloudy or has separated into layers.
Phytomenadione 10mg/1ml Injections are primarily used to:
Treat and prevent Hemorrhagic Disease of the Newborn (Vitamin K Deficiency Bleeding)
Rapidly reverse the effects of an overdose of oral anticoagulants (such as Warfarin)
Manage bleeding associated with Vitamin K deficiency caused by malabsorption (e.g., Obstructive Jaundice or Sprue)
Stabilize patients with severe liver disease who have low prothrombin levels
Prevent bleeding complications before emergency surgery in patients on blood thinners
Treat hypoprothrombinemia caused by long-term antibiotic therapy that kills Vitamin K-producing gut bacteria
This product is suitable for:
Newborn infants (as a routine preventative dose shortly after birth)
Adults experiencing life-threatening bleeding or dangerously high INR levels due to Warfarin
Patients with chronic gallbladder or liver issues requiring clotting support
Not recommended for: Routine use in patients with a known hypersensitivity to Phytomenadione or the castor oil-based solubilizers used in some formulations. It is strictly ineffective for reversing the effects of Heparin or newer oral anticoagulants like Rivaroxaban (Xarelto). Consult our pharmacist if the patient has a mechanical heart valve, as reversing their anticoagulation too quickly can increase the risk of a blood clot on the valve.
Administered strictly by a healthcare professional via intramuscular (IM), subcutaneous (SC), or slow intravenous (IV) injection
For Newborns: A single dose (usually 1mg) is given IM shortly after birth to prevent brain or internal bleeding
For Adult Warfarin Reversal: 2.5mg to 10mg is typically administered, depending on the severity of the bleeding and the INR level
The "Slow" Rule: If given IV, the injection should take at least 30 to 60 seconds to minimize the risk of a reaction
Monitoring: For adults, the INR (clotting time) should be checked 6 to 12 hours after the injection to ensure the bleeding risk is decreasing
Do not mix Phytomenadione in the same syringe with other medications
Phytomenadione is generally very safe, but some individuals may experience:
Pain, redness, or swelling at the injection site (common with IM use)
A temporary "flushed" feeling or sweating
A strange taste in the mouth (metallic or nutty)
Rare: "Derrmathillitis" (a delayed skin reaction at the injection site)
Rare but serious: Severe allergic reaction (chest tightness, difficulty breathing, or low blood pressure)
Rare: Yellowing of the skin (jaundice) in premature infants if very high doses are used
Seek immediate emergency intervention if the patient experiences sudden wheezing, a rapid pulse, or swelling of the face and throat during or after the injection.
Reputable specialized pharmaceutical firms (such as Roche/Cheplapharm or quality generic providers) – These manufacturers ensure the Vitamin K1 is stabilized in a sterile, light-protected aqueous or oily medium for reliable clinical action.
100% authentic emergency medication sourced directly from authorized and regulated distributors
Guaranteed high-quality ampoules stored in optimal, light-protected conditions to ensure full potency
Professional counseling from licensed pharmacists on the correct dosing for pediatric and adult patients
Fast and reliable delivery to your clinic, hospital, or maternity center across Nigeria
Why does my baby need this shot right after birth?
Babies are born with very low levels of Vitamin K because it does not cross the placenta well. Without this injection, some babies can develop "Vitamin K Deficiency Bleeding," which can cause dangerous bleeding in the brain or gut. One small shot prevents this entirely.
How fast does it work for someone on Warfarin?
While the injection starts working quickly, it takes the liver about 6 to 12 hours to manufacture enough new clotting factors to stop the bleeding. In an extreme emergency, a blood transfusion (Fresh Frozen Plasma) is often given alongside Vitamin K.
Can I just take Vitamin K tablets instead?
For minor issues, tablets are fine. However, in an emergency or for newborns, the injection is used because it is absorbed 100% and works much faster than a pill.
Where can I purchase Phytomenadione 10mg/1ml in Nigeria?
Hospitals and clinics can source verified Phytomenadione injections through Sanlive Pharmacy & Stores for guaranteed product integrity and professional clinical support.
No reviews yet.
Login to write a review.
Related Products
