Tazocin is a high-potency injectable antibiotic containing Piperacillin Sodium and Tazobactam Sodium. It belongs to the class of penicillin combinations known as beta-lactamase inhibitors. Piperacillin works by interfering with the bacterial cell wall synthesis, while Tazobactam acts as a "shield," protecting the Piperacillin from being destroyed by beta-lactamase enzymes produced by resistant bacteria. This synergistic action makes Tazocin effective against an exceptionally wide range of aerobic and anaerobic Gram-positive and Gram-negative bacteria.
Product Type: Penicillin / Beta-lactamase Inhibitor Combination
Active Ingredients: Piperacillin (4g) + Tazobactam (0.5g)
Manufacturer: Pfizer (Original Brand) / Generic Equivalents Available
Pack Size: Single-use 4.5g Powder in a Glass Vial
Route: Intravenous (IV) Infusion Only
Availability: Strictly Prescription Required (POM) — Hospital/Clinical Use Only
Suitable For: Adults and Children (over 2 years) with severe infections
Tazocin is a "heavy-duty" antibiotic reserved for serious, complex infections:
Severe Pneumonia: Including hospital-acquired (nosocomial) and ventilator-associated pneumonia.
Complicated Urinary Tract Infections (cUTI): Treating resistant kidney infections (pyelonephritis).
Intra-abdominal Infections: Managing peritonitis or complex infections of the appendix and gallbladder.
Skin and Soft Tissue Infections: Treating infected diabetic foot ulcers and severe cellulitis.
Bacterial Sepsis: Treating life-threatening bloodstream infections.
Febrile Neutropenia: Managing suspected bacterial infections in patients with dangerously low white blood cell counts (e.g., during chemotherapy).
Penicillin Allergy: Do not use if you have a history of severe allergic reactions (anaphylaxis) to Penicillins, Cephalosporins, or other beta-lactam antibiotics. Kidney Function: Dosing must be adjusted for patients with renal impairment to prevent drug accumulation and neurological toxicity (seizures). C. Diff Alert: Like all strong antibiotics, Tazocin can lead to severe Clostridioides difficile-associated diarrhea. Notify the medical team immediately if watery or bloody stools occur. Bleeding Risk: In some patients, especially those with kidney failure, Tazocin can affect blood clotting (platelet aggregation). Sodium Content: Each 4.5g vial contains approximately 9.39 mmol (216 mg) of sodium; this must be considered for patients on salt-restricted diets.
Tazocin must be prepared and administered by a qualified healthcare professional in a clinical setting.
Administration Protocols:
Reconstitution: The 4.5g powder is dissolved with 20ml of a compatible diluent (like 0.9% Normal Saline or Sterile Water for Injection).
Dilution: The reconstituted solution is further diluted in a 50ml to 150ml IV bag.
Infusion Rate: Administer via IV infusion over 30 minutes.
Extended Infusion: In some critical care settings, doctors may prescribe an "extended infusion" over 3 to 4 hours to improve the drug's efficacy against resistant bacteria.
Compatibility: Tazocin is incompatible with Aminoglycosides (like Gentamicin) and should not be mixed in the same IV bag or line.
Common side effects include diarrhea, nausea, vomiting, and skin rash. Some patients may experience headache, insomnia, or inflammation at the injection site. If you develop a severe, peeling skin rash (Stevens-Johnson Syndrome), sudden swelling of the face, or difficulty breathing, seek emergency intervention immediately.
Store the dry powder vials at room temperature below 25°C, protected from light. Once reconstituted, the solution should be used immediately. If necessary, it can be stored for up to 24 hours in a refrigerator ($2^\circ\text{C}$ to $8^\circ\text{C}$). Keep out of reach of children.
Q: Can I take this for a "Viral Infection"?
A: No. Tazocin is strictly for bacterial infections. It will not work for the common cold, flu, or COVID-19.
Q: Why is it called "4.5g" if it only has 4g of Piperacillin?
A: The "4.5g" refers to the combined weight of both active ingredients: 4g of Piperacillin plus 0.5g of Tazobactam.
Q: Is it safe during "Pregnancy"?
A: There are no adequate studies in pregnant women. It should only be used if the potential benefit clearly outweighs the risk to the fetus.
Q: Can it be given as an "IM" (Intramuscular) injection?
A: No. Tazocin 4.5g is specifically formulated for Intravenous (IV) use only.
Authentic Tazocin 4.5g (by Pfizer) is supplied by Sanlive Pharmacy to registered hospitals and intensive care units. We maintain strict pharmaceutical handling standards to ensure the potency of this critical broad-spectrum antibiotic.
Authentic Pfizer (Original) clinical-grade stock.
Expert support for hospital-level dosing and reconstitution.
Licensed pharmacists available for drug-allergy and renal-safety checks.
Fast, secure delivery to medical facilities across Nigeria.
Order Tazocin 4.5g from Sanlive Pharmacy today for professional-grade, life-saving bacterial control.
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