Xeljanz contains Tofacitinib, a breakthrough oral medication belonging to a class of drugs known as Janus Kinase (JAK) inhibitors. Unlike traditional biologics that are injected, Xeljanz is a small-molecule drug taken as a tablet. It works by blocking specific pathways (JAK1 and JAK3) inside immune cells, effectively "turning down" the overactive signals that cause chronic inflammation and tissue damage. It is a primary therapy for patients who have not responded well to standard treatments like Methotrexate.
Product Type: DMARD (Disease-Modifying Antirheumatic Drug) / JAK Inhibitor
Active Ingredient: Tofacitinib Citrate (5mg)
Manufacturer: Pfizer (Original Brand)
Pack Size: 28 or 60 Tablets
Route: Oral
Availability: Strictly Prescription Required (POM) — Specialist (Rheumatologist/Gastroenterologist) consultation mandatory
Suitable For: Adults with moderate to severe inflammatory conditions
Xeljanz is used to treat chronic, immune-mediated inflammatory diseases:
Rheumatoid Arthritis (RA): Reducing joint pain, swelling, and stiffness when other medicines haven't worked.
Psoriatic Arthritis (PsA): Managing joint inflammation and skin symptoms in patients with psoriasis.
Ulcerative Colitis (UC): Treating moderate to severe inflammation of the colon and rectum to achieve and maintain remission.
Ankylosing Spondylitis (AS): Reducing inflammation in the spine and large joints.
Polyarticular Juvenile Idiopathic Arthritis: Specific dosing for children 2 years and older.
Serious Infections: Xeljanz lowers your immune system's ability to fight infections. You must be tested for Tuberculosis (TB) before starting. Blood Clots: There is an increased risk of blood clots in the lungs (Pulmonary Embolism) and deep veins, especially at higher doses or in patients with heart risk factors. Heart Health: Clinical trials have shown an increased risk of major heart-related events (heart attack/stroke) and certain cancers (like lymphoma and lung cancer) in some patients. Shingles Alert: There is a higher risk of developing Herpes Zoster (Shingles). Consult your doctor about the Shingles vaccine before starting. Tummy Tears: Perforation (tears) in the stomach or intestines can occur, especially in patients taking NSAIDs or Steroids.
For maximum efficacy, Xeljanz must be taken consistently as part of a long-term treatment plan.
Standard Dosage:
Adults (RA/PsA): Typically one 5mg tablet twice daily.
Ulcerative Colitis: Often begins with a higher induction dose (10mg) before moving to 5mg maintenance.
Application Tips:
With or Without Food: Xeljanz can be taken at any time of day, regardless of meal times.
Swallow Whole: Do not crush, split, or chew the tablet.
Monitoring: Your doctor will require regular blood tests to monitor your liver enzymes, cholesterol, and white blood cell counts.
Infection Check: If you develop a fever, chills, or a persistent cough, stop the medication and notify your specialist immediately.
Common side effects include upper respiratory tract infections (common cold/sinusitis), headache, diarrhea, and high blood pressure. Some patients may notice an increase in cholesterol levels. If you experience sudden shortness of breath, chest pain, or swelling in one leg (signs of a blood clot), seek emergency medical care immediately.
Store in a cool, dry place below 30°C, protected from moisture. Keep the tablets in their original Pfizer bottle or blister pack to maintain stability. Keep out of reach of children.
Q: Can I take Xeljanz while "Pregnant"?
A: No. Xeljanz may harm an unborn baby. Effective contraception must be used during treatment and for at least 4 weeks after the last dose.
Q: Is this a "Steroid"?
A: No. Xeljanz is a JAK inhibitor. While it reduces inflammation like a steroid, it works on a much more specific cellular level and is intended for long-term use.
Q: Can I get "Vaccinated" while on Xeljanz?
A: You should avoid "live" vaccines (like Yellow Fever or Measles). Always consult your pharmacist or doctor before receiving any vaccination.
Q: How long until I feel better?
A: Some patients feel a reduction in joint pain in as little as 2 to 4 weeks, though the full effect on inflammation may take up to 3 to 6 months.
Authentic Xeljanz 5mg (by Pfizer) is available at Sanlive Pharmacy. Given the specialized nature of JAK inhibitors, we provide a full clinical screening for potential drug interactions and coordinate with your specialist to ensure your safety monitoring is up to date.
Authentic Pfizer (Original) premium specialty stock.
Expert guidance on infection prevention and safety monitoring.
Licensed pharmacists available for complex immunological consultations.
Fast, secure delivery of specialty medications across Nigeria.
Order Xeljanz 5mg from Sanlive Pharmacy today for professional-grade management of chronic inflammatory conditions.
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