GSUNATE INJECTION — GOLD STANDARD FOR SEVERE MALARIA TREATMENT

Gsunate Injection is a life-saving antimalarial containing Artesunate. It is a water-soluble hemisuccinate derivative of artemisinin. Recognized by the World Health Organization (WHO) as the first-line treatment for severe malaria, Gsunate works with extreme speed to kill malaria parasites (Plasmodium falciparum) in the blood. Because it can be administered intravenously, it reaches peak concentration almost instantly, making it the critical choice for patients who are unconscious, convulsing, or unable to tolerate oral medication.

• Product Type: Artemisinin-Derivative Antimalarial (Injectable)

• Active Ingredient: Artesunate (60mg)

• Manufacturer: Guilin Pharmaceutical (Original WHO-Prequalified Manufacturer)

• Pack Size: 1 Vial (Powder) + 1 Ampoule (Sodium Bicarbonate Solvent) + 1 Ampoule (Sodium Chloride Diluent)

• Route: Intravenous (IV) or Intramuscular (IM)

• Availability: Strictly Prescription Required (POM) — Hospital Use Only

• Suitable For: Adults and Children with severe/complicated malaria

What Is Gsunate 60mg Used For?

Gsunate is the "emergency" intervention for malaria cases that have become life-threatening:

1. Severe Falciparum Malaria: Rapidly reducing exceptionally high parasite counts to prevent multi-organ failure.

2. Cerebral Malaria: Treating infections that have caused coma, altered consciousness, or repeated seizures.

3. Severe Anemia/Jaundice: Managing malaria complicated by the massive destruction of red blood cells.

4. Inability to Swallow: Providing a reliable treatment for patients who are vomiting persistently or are too weak to take tablets.

⚠️ Critical Safety Warning

Preparation Protocol: Artesunate powder is unstable once mixed. It must be prepared immediately before use and discarded if not used within one hour. Follow-Up Therapy: Gsunate is meant to stabilize the patient. Once the patient can swallow (usually after 24–48 hours), they must complete a full 3-day course of an oral Artemisinin-based Combination Therapy (ACT) like Lonart or Coartem to ensure the malaria does not return. Delayed Hemolysis: In rare cases, a drop in red blood cells (anemia) can occur 1 to 3 weeks after treatment. Patients should be monitored for paleness or extreme fatigue post-recovery.

How to Administer

Gsunate must be administered by a qualified healthcare professional.

Administration Steps:

1. Reconstitution: Dissolve the 60mg powder with the provided 5% Sodium Bicarbonate ampoule (0.6ml) and shake until clear.

2. Dilution:

   • For IV: Add 5ml of Normal Saline or 5% Dextrose. Inject slowly over 1–2 minutes.

   • For IM: Add 2ml of Normal Saline or 5% Dextrose. Inject deeply into the buttock.

3. Dosing Schedule: Usually administered at 0, 12, and 24 hours, followed by once-daily doses until the patient can switch to oral medication.

Common Side Effects

Gsunate is remarkably well-tolerated. Some patients may experience a temporary metallic taste, dizziness, or a mild skin rash. Pain at the injection site is common with IM administration. If the patient develops dark-colored urine or yellowing of the eyes several days after treatment, consult a doctor immediately.

Storage Instructions

Store the unmixed vial in a cool, dry place below 30°C, protected from light. Do not use if the powder has changed color or if the reconstituted solution is cloudy. Keep out of reach of children.

Frequently Asked Questions (FAQ)

Q: Is "Gsunate" better than "Quinine" injections?

A: Yes. Clinical trials (SEAQUAMAT/AQUAMAT) proved that Artesunate (Gsunate) significantly reduces the risk of death compared to Quinine and has fewer side effects (no hearing loss or severe low blood sugar).

Q: Can it be used in the first trimester of pregnancy?

A: WHO guidelines state that for severe malaria, the benefit of saving the mother's life with Artesunate outweighs the risks, regardless of the trimester.

Q: Why do I need tablets after the injection?

A: The injection kills parasites very quickly, but some "sleepy" parasites may remain. The 3-day oral ACT course acts as a "mop-up" to ensure a 100% cure rate.

Purchase Notice at Sanlive Pharmacy

Authentic Gsunate 60mg (by Guilin Pharma) is supplied by Sanlive Pharmacy to hospitals and clinics. We guarantee the authenticity of our antimalarials, ensuring they are the WHO-prequalified versions required for the highest standard of care.

Why Buy from Sanlive Pharmacy?

• Authentic Guilin Pharmaceutical (Original) stock.

• Expert clinical support for reconstitution and dosing.

• Licensed pharmacists available for emergency facility supply.

• Fast, specialized delivery to medical centers across Nigeria.

Order Gsunate 60mg from Sanlive Pharmacy today for professional-grade, life-saving malaria intervention.